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Treatment of Seizures in Neonate With HIE
Sponsor: Mansoura University
Summary
Aim of the study To evaluate and compare phenobarbital's and levetiracetam's safety and efficacy for treating seizures in neonates with moderate to severe HIE
Official title: Treatment of Seizures in Neonate With Hypoxic Ischemic Encephalopathy
Key Details
Gender
All
Age Range
1 Day - 30 Days
Study Type
INTERVENTIONAL
Enrollment
66
Start Date
2026-01-01
Completion Date
2026-10
Last Updated
2025-12-16
Healthy Volunteers
No
Interventions
Phenobarbital
Phenobarbital is strongly recommended by the World Health Organization as the first-line treatment of neonatal seizures and is the standard of care at most institutions
Levetiracetam
levetiracetam has emerged as an alternative Anti-seizure medication that may offer improved safety and tolerability profiles.
Locations (2)
University Children's Hospital, Mansoura University
Al Mansurah, Egypt
Al Galaa Teaching Hospital
Cairo, Egypt