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RECRUITING
NCT07284563
PHASE2

Ultralow Dose PET Imaging for 18F-NaF Uptake

Sponsor: Akiva Mintz

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to evaluate an investigational ultralow dose positron emission tomography (PET imaging) technique for increased bone turnover that is found in diseases such as cancer, trauma, infection, arthritis, and other benign diseases of bone detection and monitoring. The main question it aims to answer is: Can the investigators optimize the timing, scan duration, and image reconstruction to reduce the radiation dose 10-100 fold of the current clinical standard? Participants will be injected with a radioactive tracer called Fluorine-18 (18F)-sodium fluoride (NaF) and be imaged on a new type of high sensitivity PET scanner for up to 3 hours.

Official title: Evaluation of Ultralow Dose PET Imaging for Detecting 18F-NaF Uptake

Key Details

Gender

All

Age Range

18 Years - 120 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2025-09-01

Completion Date

2030-06-30

Last Updated

2025-12-16

Healthy Volunteers

Yes

Interventions

DRUG

18F-NaF

Participants will be injected with 18F-NaF and imaged for up to 3 hours on a PET scanner

Locations (2)

Nuclear Imaging Institute

Englewood, New Jersey, United States

Nuclear Imaging Institute

Englewood, New Jersey, United States