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Ultralow Dose PET Imaging of 18F-flurpiridaz
Sponsor: Akiva Mintz
Summary
The goal of this clinical trial is to evaluate an investigational ultralow dose positron emission tomography (PET) imaging technique for known or suspected coronary artery disease (for detecting myocardial ischemia or infarction) detection and monitoring. The main question it aims to answer is: Can the investigators optimize the timing, scan duration, and image reconstruction to reduce the radiation dose 10-100 fold of the current clinical standard? Participants will be injected with a radioactive tracer called Fluorine-18 (18F)-flurpiridaz and be imaged on a new type of high sensitivity PET scanner for up to 3 hours
Official title: Evaluation of 0.25mCi PET Imaging for Detecting Cardiac Perfusion
Key Details
Gender
All
Age Range
18 Years - 120 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2025-12
Completion Date
2030-06-30
Last Updated
2025-12-16
Healthy Volunteers
Yes
Interventions
18F-flurpiridaz
Participants will be injected with 18F-flurpiridaz and imaged for up to 3 hours on a PET scanner
Locations (1)
Nuclear Imaging Institute
Englewood, New Jersey, United States