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RECRUITING
NCT07285083
NA

Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery

Sponsor: Sheikh Zayed Medical College

View on ClinicalTrials.gov

Summary

This study investigates the effectiveness of adding dexmedetomidine to bupivacaine for postoperative analgesia in patients undergoing abdominal surgeries. The research compares pain relief in two groups: one receiving a combination of bupivacaine and dexmedetomidine via a transversus abdominis plane (TAP) block, and the other receiving bupivacaine alone. The study aims to evaluate whether dexmedetomidine enhances pain relief, reduces the need for additional pain medication, and impacts sedation and side effects such as hypotension, bradycardia, and nausea. Conducted at Sheikh Zayed Medical College in Rahim Yar Khan, Pakistan, the trial will involve 80 participants and will measure pain using the Visual Analogue Scale (VAS), along with monitoring other vital parameters and complications over 12 hours post-surgery. The primary objective is to determine if the addition of dexmedetomidine provides superior pain control without significantly increasing side effects.

Official title: Comparison of Pain Relief by Bupivacaine With Dexmedetomidine and Bupivacaine Alone in Transversus Abdominis Plane Block for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries.

Key Details

Gender

All

Age Range

21 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2024-08-01

Completion Date

2025-12

Last Updated

2025-12-22

Healthy Volunteers

No

Interventions

DRUG

Bupivacaine with Dexmedetomidine (TAP Block)

A combination of 0.25% bupivacaine and 1 mcg/kg dexmedetomidine administered bilaterally via ultrasound-guided transversus abdominis plane (TAP) block to provide postoperative analgesia for abdominal surgery

DRUG

Bupivacaine (TAP Block)

10 ml of 0.25% bupivacaine administered bilaterally via ultrasound-guided transversus abdominis plane (TAP) block to provide postoperative analgesia for abdominal surgery

Locations (1)

Sheikh Zayed Medical College

Rahim Yar Khan, Punjab Province, Pakistan