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A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia (ExCIT)
Sponsor: Jiangsu HengRui Medicine Co., Ltd.
Summary
The ExCIT study is being conducted to evaluate the efficacy, and safety of of Hetrombopag Olamine Tablets Vs Placebo in Patients with Chemotherapy-Induced Thrombocytopenia.
Official title: A Randomized, Multi-Center, Double-Blind, Phase III Study Evaluating the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2026-04-16
Completion Date
2029-06
Last Updated
2026-10-01
Healthy Volunteers
No
Interventions
Hetrombopag Olamine
For Part A, all participants would receive hetrombopag treatment.
Hetrombopag Olamine; Hetrombopag Olamine Placebo
For Part B, participants would be randomized to receive hetrombopag treatment or matching placebo, respectively.
Locations (51)
Starling Oncology
Long Beach, California, United States
Cancer and Blood Specialty Clinic
Los Alamitos, California, United States
UCLA
Los Angeles, California, United States
Clermont Oncology Center
Clermont, Florida, United States
Oncology & Hematology Associates of West Broward
Coral Springs, Florida, United States
Starling Oncology / Oncology Institute of Hope & Innovation
Miami, Florida, United States
Mid-Florida Hematology & Oncology Centers, P.A.
Orange City, Florida, United States
Springfield Clinic
Springfield, Illinois, United States
University of Iowa
Iowa City, Iowa, United States
Hattiesburg Clinic Hematology/Oncology
Hattiesburg, Mississippi, United States
Cancer Partners of Nebraska
Lincoln, Nebraska, United States
Morristown Medical Center
Morristown, New Jersey, United States
MSK Cancer Center
New York, New York, United States
New York Cancer and Blood Specialists One Oncology
Shirley, New York, United States
ARENSIA Exploratory Medicine at "MBAL Sveta Sofia"
Sofia, Bulgaria
UMHAT "Sv. Ivan Rilski", EAD
Sofia, Bulgaria
Hong Kong United Oncology Centre
Hong Kong, Hong Kong, China
The Chinese University of Hong Kong
Hong Kong, Hong Kong, China
The University of Hong Kong
Hong Kong, Hong Kong, China
Gustave Roussy Cancer Campus
Clémont, France
Centre Hospitalier Lyon Sud
Lyon, France
Groupe Hospitalier Pitie-Salpetriere
Paris, France
Istituto Tumori Giovanni Paolo II IRCCS Ospedale Oncologico Bari
Bari, Italy
Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda)
Milan, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Italy
Fondazione IRCCS Policlinico San Matteo
Pavia, Italy
Szpital Specjalistyczny w Brzozowie Podkarpacki Ośrodek Onkologiczny im. ks. B. Markiewicza
Brzozów, Poland
Uniwersytecki Szpital Kliniczny w Poznaniu, Klinika Onkologii
Poznan, Poland
Institutul Oncologic Bucuresti Prof Dr. Al. Trestioreanu with SC Arensia Exploratory Medicine
Bucharest, Romania
Institute of Oncology "Ioan Chiricuta" Cluj-Napoca, Arensia Exploratory Medicine
Cluj-Napoca, Romania
Centrul de Oncologie Sfantul Nectarie Craiova
Craiova, Romania
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Seoul National University Hospital
Seoul, South Korea
Asan Medical Center
Seoul, South Korea
Pratia ES Sirius Barcelona
Barcelona, Spain
Hospital Universitario Reina Sofía Córdoba
Córdoba, Spain
Hospital Universitari Arnau de Vilanova
Lleida, Spain
Hospital Universitario HM Madrid Sanchinarro
Madrid, Spain
Hospital Universitario Ramón y Cajal
Madrid, Spain
Pratia ES Hospital Universitario de Torrejon
Madrid, Spain
Complejo Hospitalario Universitario de Orense
Ourense, Spain
Hospital Universitario General de Cataluña
Sant Cugat del Vallès, Spain
Ankara Univ Cebeci Hospital Medical Oncology
Mamak, Ankara, Turkey (Türkiye)
Istanbul Univ. Cerrahpasa Medical Faculty Hosp.
Fatih, Istanbul, Turkey (Türkiye)
Goztepe Prof. Dr. Suleyman Yalcin City Hospital
Kadıköy, Istanbul, Turkey (Türkiye)
Marmara University Pendik Training and Research Hospital
Pendik, Istanbul, Turkey (Türkiye)
I.E.U. Medicalpoint Izmir Hospital
Izmir, Turkey (Türkiye)
Pamukkale University Hospital
Kınıklı, Turkey (Türkiye)
Sakarya Univ. Training & Research Hosp. Oncology
Sakarya, Turkey (Türkiye)
Ankara Oncology TRH Clinical Research Center
Yenimahalle, Turkey (Türkiye)
ARENSIA Exploratory Medicine LLC
Kyiv, Ukraine