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Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis
Sponsor: Takeda
Summary
Psoriatic arthritis (PsA) is a long-term inflammatory disease that affects the joints and skin. The purpose of this study is to check how safe zasocitinib is, how well it is tolerated and how well it works in adults with PsA over a longer period of time. Adults who completed the 1-year (52-week) treatment period in one of the parent studies (TAK-279-PsA-3001 \[NCT06671483\] or TAK-279-PsA-3002 \[NCT06671496\]) may be able to join this continuation study (also called long-term extension or LTE study). All participants in this continuation study, will receive zasocitinib (lower or higher dose), once a day (QD). Each participant can be in this study for approximately 2 years (108 weeks). This includes a treatment period of up to 2 years (104 weeks) and a 1-month (4-week) follow-up period to monitor a participant's health.
Official title: A Phase 3, Multicenter, Long-Term Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of Zasocitinib (TAK-279) in Subjects With Active Psoriatic Arthritis Who Are Either Biologic DMARD-Naïve or Biologic DMARD-Experienced, Including Those With Inadequate Response to Biologic DMARDs
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1182
Start Date
2026-03-11
Completion Date
2029-12-18
Last Updated
2026-06-17
Healthy Volunteers
No
Conditions
Interventions
Zasocitinib
Zasocitinib oral tablets.
Locations (16)
First OC Dermatology Research Inc.
Fountain Valley, California, United States
The Cohen Medical Centers
Thousand Oaks, California, United States
Denver Arthritis Clinic - Lowry
Denver, Colorado, United States
Direct Helpers Research Center
Hialeah, Florida, United States
IRIS Research and Development
Plantation, Florida, United States
Klein and Associates, M.D., P.A.
Hagerstown, Maryland, United States
Paramount Medical Research & Consulting, LLC
Middleburg Heights, Ohio, United States
West Tennessee Research Institute
Jackson, Tennessee, United States
Accurate Clinical Research
Baytown, Texas, United States
Novel Research LLC
Bellaire, Texas, United States
Northwest Houston Arthritis Center
Houston, Texas, United States
West Texas Clinical Research
Lubbock, Texas, United States
Mie University Hospital
Tsu, Mie, Mie-ken, Japan
St. Luke's International Hospital
Chuo-ku, Tokyo, Japan
National Hospital Organization Tokyo Medical Center
Meguro-Ku, Tokyo, Japan
Centro Reumatologico de Caguas
Caguas, Puerto Rico