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RECRUITING
NCT07287280

Comparing CCI and POSSUM for Predicting Oncogynecologic Surgery Complications

Sponsor: Mahidol University

View on ClinicalTrials.gov

Summary

With the global rates of gynecologic cancers on the rise, optimizing perioperative care is imperative. Accurate risk prediction is essential for enhancing patient care, directing preoperative interventions, and facilitating informed decision-making in oncology. This research compares two widely-used risk assessment tools: the Charlson Comorbidity Index (CCI) and the Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM), in predicting perioperative outcomes. The CCI predominantly addresses comorbidities, providing simplicity and broad applicability, while POSSUM incorporates both physiological and operative factors for a more comprehensive risk assessment. Despite their application across various surgical specialties, the specific utility of these tools in onco-gynecologic surgery remains insufficiently explored. The study aims to evaluate the effectiveness of CCI and POSSUM in predicting perioperative complications, with a focus on the incidence of these complications, length of hospital stay, and 30-day mortality. The implementation of these risk tools may enhance multidisciplinary risk management, thus improving patient outcomes in gynecologic oncology surgery.

Official title: A Comparison of the Charlson Comorbidity Index (CCI) vs POSSUM Score for Prediction of Perioperative Complications in Patients Undergoing Oncogynecologic Surgery

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2025-09-01

Completion Date

2027-10-31

Last Updated

2025-12-17

Healthy Volunteers

No

Interventions

OTHER

CCI score

Charlson comorbidity index included age and medical conditions

OTHER

POSSUM score

POSSUM included physical status and laboratory investigation

Locations (1)

Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok, Thailand