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Effects of BLa80 and LRa05 on the Gut Microbiota Metabolite Profile of Healthy Individuals
Sponsor: Wecare Probiotics Co., Ltd.
Summary
Gut microbiota play a key role in polyphenol metabolism, participating in the breakdown of dietary components and producing various small molecule metabolites that affect human health. However, little is currently known about how gut microbes metabolize dietary compounds and produce bioactive metabolites. This study aims to use metabolomics to precisely identify food-derived metabolites in the blood to investigate whether probiotics (BLa80, LRa05) can enhance the breakdown of dietary components and improve their absorption and utilization in the human body.
Official title: Effects of BLa80 and LRa05 on the Gut Microbiota Metabolite Profile of Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
375
Start Date
2025-12-10
Completion Date
2026-11-15
Last Updated
2025-12-17
Healthy Volunteers
Yes
Conditions
Interventions
Placebo
The experimental phase of this study will last 8 weeks and each subject will receive 3 follow-up visits (week 0, week 4, week 8).
BLa80
The experimental phase of this study will last 8 weeks and each subject will receive 3 follow-up visits (week 0, week 4, week 8).
LRa05
The experimental phase of this study will last 8 weeks and each subject will receive 3 follow-up visits (week 0, week 4, week 8).
Locations (1)
The First Affiliated Hospttal, Sun Yat-sen University
Guangzhou, Guangdong, China