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Application of Growth Factors Derived From Platelets to Accelerate Healing and Reduce Post-extraction Complications in Diabetic Individuals
Sponsor: King Abdulaziz University
Summary
To evaluate soft tissue closure in diabetic extraction sockets using digital scans. To compare healing between sockets treated with Advanced Platelet Rich Fibrin (A-PRF) vs. untreated control sites. To assess post-operative discomfort and patient satisfaction.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2025-12-01
Completion Date
2026-09-30
Last Updated
2025-12-17
Healthy Volunteers
No
Conditions
Interventions
Platelet rich fibrin
Description: A-PRF is a biologically active scaffold that fits into the proven principles of the physiology of the wound-healing process. Its action lies in the controlled and prolonged release of fundamental factors like the PDGF (platelet-derived growth factor), TGF-β (transforming growth factor beta), and VEGF (vascular endothelial growth factor) which collectively enhance cellular migration, angiogenic events, and extracellular matrix remodeling factors of repair in the recovery of the tissues.
Locations (1)
King AbdulAziz University
Jeddah, Mekkah, Saudi Arabia