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Post-Intensive Care Syndrome - Multicentre Prospective Registry Database of the DACH Region
Sponsor: Medical University of Vienna
Summary
Post-Intensive Care Syndrome (PICS) refers to long-term cognitive, physical, and psychological impairments that can arise after intensive care treatment. These symptoms may begin within 24 hours of ICU admission and persist for years. Affected patients and their families (PICS-F) face significant burdens, with up to 94% of relatives impacted. Given its high prevalence and socioeconomic impact, this prospective registry study aims to identify risk factors and long-term consequences of PICS and PICS-F. The study consists of six modules, starting with data collection during ICU stays and continuing with follow-ups at various intervals post-discharge (up to five years). The primary goal is to investigate diagnostic and therapeutic strategies, while secondary objectives include identifying risk factors, determining impairment severity, and exploring biological mechanisms. Standardized questionnaires and biological samples (blood) are used for data collection.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
5000
Start Date
2026-02-04
Completion Date
2035-11-01
Last Updated
2026-02-19
Healthy Volunteers
No
Locations (4)
Medical University of Vienna
Vienna, Vienna, Austria
Universitätsklinikum Augsburg
Augsburg, Bavaria, Germany
Universitätsklinikum Würzburg
Würzburg, Bavaria, Germany
Charité - Universitätsmedizin Berlin
Berlin, State of Berlin, Germany