Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)
Sponsor: Bristol-Myers Squibb
Summary
The purpose of this study is to evaluate the safety and tolerability of Pumitamig alone or in combination with Ipilimumab in participants with first-line advanced or unresectable Hepatocellular Carcinoma (HCC)
Official title: ROSETTA HCC-206: An Open-Label, Multi-Center, Randomized Phase 1/2 Study of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
129
Start Date
2026-03-16
Completion Date
2031-10-14
Last Updated
2026-05-14
Healthy Volunteers
No
Conditions
Interventions
Pumitamig
Specified dose on specified days
Ipilimumab
Specified dose on specified days
Atezolizumab
Specified dose on specified days
Bevacizumab
Specified dose on specified days
Locations (50)
Local Institution - 0070
Los Angeles, California, United States
Local Institution - 0107
Chicago, Illinois, United States
John Theurer Cancer Center at Hackensack University Medical Center
Hackensack, New Jersey, United States
Local Institution - 0100
Mineola, New York, United States
Providence Portland Medical Center
Portland, Oregon, United States
Providence St. Vincent Medical Center
Portland, Oregon, United States
Tennessee Oncology
Nashville, Tennessee, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
Local Institution - 0083
Seattle, Washington, United States
Royal Prince Alfred Hospital
Camperdown, New South Wales, Australia
Local Institution - 0033
Westmead, New South Wales, Australia
Sunshine Coast University Hospital
Birtinya, Queensland, Australia
The Royal Melbourne Hospital
Parkville, Victoria, Australia
Bradfordhill
Santiago, Santiago Metropolitan, Chile
Local Institution - 0106
Santiago Region Metropolitana, Santiago Metropolitan, Chile
Local Institution - 0075
Guangzhou, Guangdong, China
Local Institution - 0086
Xi'an, Shaanxi, China
Local Institution - 0078
Shanghai, Shanghai Municipality, China
Local Institution - 0056
Pessac, Aquitaine, France
Local Institution - 0004
Grenoble, Isère, France
Local Institution - 0001
Montpellier, Languedoc-Roussillon, France
Local Institution - 0018
Saint Priest En Jarez, Pays de la Loire Region, France
Local Institution - 0003
Bobigny, France
Local Institution - 0031
Cologne, North Rhine-Westphalia, Germany
Local Institution - 0028
Kiel, Schleswig-Holstein, Germany
Local Institution - 0030
Frankfurt, Germany
Local Institution - 0109
Pisa, Tuscany, Italy
Local Institution - 0088
Milan, Italy
Local Institution - 0089
Milan, Italy
Local Institution - 0016
Pisa, Italy
Local Institution - 0046
Rozzano (MI), Italy
Local Institution - 0021
Wroclaw, Lower Silesian Voivodeship, Poland
Local Institution - 0105
Warsaw, Masovian Voivodeship, Poland
Local Institution - 0020
Gdansk, Poland
Local Institution - 0009
Singapore, Singapore
Local Institution - 0012
Singapore, Singapore
Local Institution - 0027
Seongnam-si, Gyeonggi-do, South Korea
Local Institution - 0013
Seoul, Seoul Teugbyeolsi, South Korea
Local Institution - 0011
Seoul, Seoul-teukbyeolsi, South Korea
Local Institution - 0014
Pamplona, Navarre, Spain
Local Institution - 0015
Barcelona, Spain
Local Institution - 0060
Madrid, Spain
Local Institution - 0095
Madrid, Spain
Local Institution - 0032
Taichung, Taiwan
National Cheng Kung University Hospital
Tainan, Taiwan
National Taiwan University Hospital
Taipei, Taiwan
Taipei Veterans General Hospital
Taipei, Taiwan
Hammersmith Hospital
London, London, City of, United Kingdom
Cancer Research UK - The Beatson Institute for Cancer Research (Cancer Research UK Beatson Laboratories)
Glasgow, South Western Scotland, United Kingdom
Local Institution - 0053
Metropolitan Borough of Wirral, United Kingdom