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Study on the Correlation Between Metabolomics and Anxiety and Depression in Bronchiectasis
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Summary
Bronchiectasis is a common lung disease. Approximately 20-40% of patients with bronchiectasis experience comorbid anxiety and depression. Multiple studies have now demonstrated that anxiety and depression are associated with an increased risk of disease exacerbation in these individuals. Therefore, this study aims to collect data on anxiety and depression status, disease exacerbation frequency, hospitalisation rates, and mortality among participants diagnosed with bronchiectasis. Concurrently, biological samples including blood, sputum, and stool will be obtained. Through metabolomics analysis, we will investigate the expression of anxiety and depression-related metabolic pathways and identify corresponding biomarkers to explore their role in the progression of bronchiectasis.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2025-12-20
Completion Date
2030-12-31
Last Updated
2025-12-18
Healthy Volunteers
No
Conditions
Interventions
inapplicable
This study is observational in nature and did not involve any intervention measures.
Locations (1)
Wuhan Union Hospital,China
Wuhan, Hubei, China