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NCT07291167

Study on the Correlation Between Metabolomics and Anxiety and Depression in Bronchiectasis

Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

View on ClinicalTrials.gov

Summary

Bronchiectasis is a common lung disease. Approximately 20-40% of patients with bronchiectasis experience comorbid anxiety and depression. Multiple studies have now demonstrated that anxiety and depression are associated with an increased risk of disease exacerbation in these individuals. Therefore, this study aims to collect data on anxiety and depression status, disease exacerbation frequency, hospitalisation rates, and mortality among participants diagnosed with bronchiectasis. Concurrently, biological samples including blood, sputum, and stool will be obtained. Through metabolomics analysis, we will investigate the expression of anxiety and depression-related metabolic pathways and identify corresponding biomarkers to explore their role in the progression of bronchiectasis.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2025-12-20

Completion Date

2030-12-31

Last Updated

2025-12-18

Healthy Volunteers

No

Conditions

Interventions

OTHER

inapplicable

This study is observational in nature and did not involve any intervention measures.

Locations (1)

Wuhan Union Hospital,China

Wuhan, Hubei, China