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Comparison of Outcome Between Grisotti Flap Versus Reverse Mirror Grisotti Flap for Central Quadrant Breast Tumors
Sponsor: Mayo Hospital Lahore
Summary
Breast conservation surgery is equivalent to mastectomy for early stage breast cancer patients. Central quadrant tumours can be treated with various oncoplastic techniques with a satisfactory aesthetic outcome and low morbidity. Grisotti flap and reverse mirror grisotti flap are the favourable viable surgical options for central quadrant breast tumours. our hypothesis is that there is a difference in the outcome between Grisotti versus Reverse Mirror Grisotti flap in centrally located breast cancers.
Key Details
Gender
FEMALE
Age Range
25 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
106
Start Date
2025-11-04
Completion Date
2026-05-04
Last Updated
2025-12-18
Healthy Volunteers
No
Conditions
Interventions
Grisotti Flap
The Grisotti flap is a local rotational flap used to reconstruct defects after removing a central breast cancer, often involving the nipple-areola complex (NAC). It uses tissue from the inferior pole of the breast to fill the central defect. The dermoglandular flap will be raised on infero-lateral perforators of intercostal arteries and will be rotated and advanced to fill the gap .
Reverse Mirror Grisotti Flap
The reverse-mirror version is a modification where the flap is flipped and reoriented, using the internal mammary vessels as the primary blood supply. The dermoglandular flap will be raised on the medial perforators of internal mammary artery and will be rotated and advanced to fill the defect.
Locations (1)
King Edward Medical University
Lahore, Punjab Province, Pakistan