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ACTIVE NOT RECRUITING
NCT07293065
PHASE3

A Phase III Clinical Trial to Evaluate Long-Term Protective Efficacy of Recombinant Zoster Vaccine (CHO Cell)

Sponsor: MAXVAX Biotechnology Limited Liability Company

View on ClinicalTrials.gov

Summary

The purpose of the sutdy is to evaluate the protective efficacy of Recombinant Herpes Zoster Vaccine (CHO Cell) (hereinafter referred to as "the investigational vaccine") in preventing herpes zoster at 13-36 months after complete immunization with the 0- and 2-month immunization schedule in individuals aged 40 years and older.

Official title: A Multicenter, Double-Blind, Placebo-Controlled Phase III Clinical Trial to Evaluate the Long-Term Protective Efficacy of Recombinant Herpes Zoster Vaccine (CHO Cell) in Adults Aged 40 Years and Above

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

12000

Start Date

2025-12-15

Completion Date

2028-12-31

Last Updated

2026-03-10

Healthy Volunteers

Yes

Conditions

Interventions

BIOLOGICAL

Recombinant Zoster Vaccine (CHO Cell)

0.5 mL per dose, containing a total of 50 µg recombinant varicella zoster virus glycoprotein E, adjuvanted with MA105. Intramuscular injection

BIOLOGICAL

NaCl solution Placebo

0.5 mL per dose, containing 4.5 mg sodium chloride. Intramuscular injection

Locations (4)

Hebei Provincial Center for Disease Control and Prevention

Shijiazhuang, Hebei, China

Henan Center for Diseases Control and Prevention

Zhengzhou, Henan, China

Hubei Provincial Center for Disease Control and Prevention

Wuhan, Hubei, China

Yunnan Center For Disease Control and Prevention

Kunming, Yunnan, China