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ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
Sponsor: argenx
Summary
ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best therapeutic approach to reduce patients' side effects and improve their quality of life.
Official title: A Master Protocol for an Exploratory, Phase 2a, Proof-of-Concept Platform Study to Evaluate the Safety, Tolerability, and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
70
Start Date
2025-12-19
Completion Date
2028-03-07
Last Updated
2026-02-18
Healthy Volunteers
No
Conditions
Interventions
Efgartigimod IV
Intravenous infusion of efgartigimod
Empasiprubart IV
Intravenous infusion of empasiprubart
Locations (5)
Profound Research LLC - Carlsbad
Carlsbad, California, United States
Visionary Investigators Network
Miami, Florida, United States
Erlanger Health System
Columbia, Maryland, United States
Dent Neurologic Institute - Amherst
Amherst, New York, United States
National Neuromuscular Research Institute
Austin, Texas, United States