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The Effective Blood Concentration of Ciprofol
Sponsor: Peking University Shenzhen Hospital
Summary
1. Eligible patients were selected and enrolled in the study. 2. General anesthesia was induced using ciprofol in all participants, with standardized evaluation of consciousness levels during induction. 3. The patients' pain and cognition are followed up after surgery.
Official title: Median Effective Concentration of Ciprofol and Its Correlation With Bispectral Index: A Prospective Observational Study
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
101
Start Date
2025-07-01
Completion Date
2026-06-30
Last Updated
2026-01-06
Healthy Volunteers
No
Conditions
Interventions
Ciprofol
Beginning with an initial target plasma concentration of ciprofol at 1.2 μg/mL. Assessments of the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale and Bispectral Index (BIS) values are performed every minute until the patient achieves a complete anesthetic state (defined as an MOAA/S score of 0).
Locations (1)
Peking University Shenzhen Hospital
Shenzhen, Guangdong, China