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NCT07299318

Multimodal Deep Learning for Lymph Node Metastasis in Thyroid Cancer

Sponsor: West China Hospital

View on ClinicalTrials.gov

Summary

Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy in clinical practice, accounting for approximately 85% of all thyroid malignancies. The occurrence of cervical lymph node metastasis further increases the risk of local tumor recurrence and distant metastasis, thereby reducing patient survival rates. Pathological examinations reveal that approximately 30-80% of PTC patients have lymph node metastasis. Early detection of metastatic lymph nodes and the development of individualized treatment plans are crucial for improving patient prognosis. Currently, the primary method for diagnosing lymph node metastasis is ultrasound-guided fine-needle aspiration, but its accuracy is limited by sample quality and carries a risk of false-negative results. In recent years, deep learning technology has demonstrated significant potential in the field of medical image analysis. Therefore, the investigators aim to develop a deep learning model based on neck ultrasound to more accurately predict lymph node metastasis.

Official title: A Multicenter Study on Developing a Multimodal Deep Learning Model Based on Color Doppler Ultrasound for Predicting Lymph Node Metastasis and Cancer Staging in Papillary Thyroid Carcinoma

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

3200

Start Date

2026-01-01

Completion Date

2026-05-01

Last Updated

2025-12-23

Healthy Volunteers

No

Interventions

OTHER

not intervention

This is a retrospective observational study in which participants will not undergo any interventions, and only data collection and analysis will be performed on the participants.

Locations (1)

West China hospital of Sichuan University

Chengdu, Sichuan, China