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ACTIVE NOT RECRUITING
NCT07302061

"Effects of Fluid Status and Regional Cerebral Oxygenation on Postoperative Cognitive Dysfunction in Patients Undergoing Lower Extremity Surgery Under General and Spinal Anesthesia."

Sponsor: Goztepe Training and Research Hospital

View on ClinicalTrials.gov

Summary

We frequently encounter cognitive impairments in patients over 65 undergoing Lower extremity surgery, depending on comorbidities and the choice of anesthesia method. The current development of neuraxial anesthesia techniques and close monitoring devices helps us prevent and detect cognitive impairment early in these patients. In this study, we aimed to investigate the effects of different anesthesia techniques (general anesthesia/spinal anesthesia) applied in orthopedic cases on patient fluid status (pleth variablity index) and regional cerebral oxygenation (NIRS), and their relationship with cognitive dysfunction.

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

OBSERVATIONAL

Enrollment

60

Start Date

2025-08-01

Completion Date

2026-01-01

Last Updated

2025-12-24

Healthy Volunteers

No

Locations (1)

Goztepe training and research hospital

Istanbul, Kadikoy, Turkey (Türkiye)