Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 2)
Sponsor: Boston Children's Hospital
Summary
Using a four-week randomized, crossover study design, we will assess the impact of 2 weeks of a high bile acid-binding blenderized diet, compared to 2 weeks of a low bile acid-binding blenderized diet, on gastric and salivary bile acid concentrations within individual participants. Four weeks of an amino acid formula will be a comparator group.
Official title: The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations: A Novel Intervention for Children at Risk for Aspiration-Associated Complications (Aim 2)
Key Details
Gender
All
Age Range
5 Years - 21 Years
Study Type
INTERVENTIONAL
Enrollment
66
Start Date
2026-07
Completion Date
2030-08
Last Updated
2025-12-26
Healthy Volunteers
No
Interventions
Low bile acid binding blenderized diet
Low bile acid binding blenderized diet administered for 2 weeks
High bile acid binding blenderized diet
High bile acid binding blenderized diet administered for 2 weeks