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The Effects of Remimazolam on Cerebral Blood Flow Following General Anesthesia Induction
Sponsor: Jun Zhang
Summary
This study will enroll 40 subjects aged 18 years or older scheduled for elective surgery under general anesthesia with endotracheal intubation. Basic medical history information will be collected. Subjects will be divided into two groups of 20 each: a remimazolam group and a propofol group. The study period will span from one day before surgery to one day after surgery. The study will assess middle cerebral artery cerebral blood flow following general anesthesia induction and postoperative anesthesia recovery.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-12-31
Completion Date
2026-02-01
Last Updated
2025-12-31
Healthy Volunteers
No
Conditions
Interventions
Remimazolam
Remimazolam is used as the sedative agent during the anesthesia induction period (administer remimazolam as an intravenous bolus of 0.3 mg/kg for induction).
Propofol (Group P)
Propofol is used as the sedative agent during the anesthesia induction period (administer propofol at 2 mg/kg for induction).
Locations (1)
Fudan University Shanghai Cancer Centre
Shanghai, China