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RECRUITING
NCT07304674

The Association Between Primary Aldosteronism and Cognitive Dysfunction

Sponsor: Xinjiang Medical University

View on ClinicalTrials.gov

Summary

The goal of this observational study is to learn about the prevalence, progression, and influencing factors of cognitive impairment in patients with primary aldosteronism (PA). The main questions it aims to answer are: 1. What is the prevalence of baseline cognitive impairment in PA patients and what factors are associated with it? 2. What is the incidence of cognitive progression in PA patients within 1 and 5 years of follow-up and what factors influence this progression? Participants who are already diagnosed with PA as part of their regular medical care will be invited to join this long-term study. They will complete regular cognitive tests, medical check-ups, and questionnaires for up to 5 years. Some participants will also have optional blood tests and brain scans to help researchers understand the causes behind any cognitive changes.

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1000

Start Date

2025-12-31

Completion Date

2031-12

Last Updated

2026-01-05

Healthy Volunteers

No

Locations (2)

The First Affiliated Hospital of Chengdu Medical College

Chengdu, Sichuan, China

The First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China