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NOT YET RECRUITING
NCT07305298

Mirabegron in Patients With Age-Related Macular Degeneration

Sponsor: University of Naples

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if Mirabegron works to treat dry AMD in patients, aged between 50 and 80 years-old, with early or moderate dry AMD and overactive bladder. The main question it aims to answer is: • Is there any change in outer retina morphology in patients treated? Researchers will compare the safety and efficacy of mirabegron versus conventional approach (Solifenacin) to treat dry AMD in patients with dry AMD and overactive bladder. Participants will: * Take Mirabegron or Solifenacin every day for 12 months * Visit the clinic once every 6 months for checkups and tests

Official title: Mirabegron in Patients With Age-Related Macular Degeneration Treated for Overactive Bladder: A Study Protocol for a Non-Randomized Prospective Controlled Trial

Key Details

Gender

All

Age Range

50 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

312

Start Date

2026-04-01

Completion Date

2026-12-01

Last Updated

2026-02-06

Healthy Volunteers

No

Interventions

DRUG

Mirabegron 50mg

Mirabegron (50mg/day per os) will be administered in patients with dry AMD and overactive bladder (MMirabegron arm)

DRUG

Solifenacin 5mg

Solifenacin (5mg/day per os) will be administered in control group (dry amd and overactive bladder)

Locations (1)

Federico II

Naples, Italy