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Mirabegron in Patients With Age-Related Macular Degeneration
Sponsor: University of Naples
Summary
The goal of this clinical trial is to learn if Mirabegron works to treat dry AMD in patients, aged between 50 and 80 years-old, with early or moderate dry AMD and overactive bladder. The main question it aims to answer is: • Is there any change in outer retina morphology in patients treated? Researchers will compare the safety and efficacy of mirabegron versus conventional approach (Solifenacin) to treat dry AMD in patients with dry AMD and overactive bladder. Participants will: * Take Mirabegron or Solifenacin every day for 12 months * Visit the clinic once every 6 months for checkups and tests
Official title: Mirabegron in Patients With Age-Related Macular Degeneration Treated for Overactive Bladder: A Study Protocol for a Non-Randomized Prospective Controlled Trial
Key Details
Gender
All
Age Range
50 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
312
Start Date
2026-04-01
Completion Date
2026-12-01
Last Updated
2026-02-06
Healthy Volunteers
No
Conditions
Interventions
Mirabegron 50mg
Mirabegron (50mg/day per os) will be administered in patients with dry AMD and overactive bladder (MMirabegron arm)
Solifenacin 5mg
Solifenacin (5mg/day per os) will be administered in control group (dry amd and overactive bladder)
Locations (1)
Federico II
Naples, Italy