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NCT07306858

CT-Based Deep Learning for Differentiating Acute and Chronic Osteoporotic Vertebral Compression Fractures

Sponsor: Xin Fan

View on ClinicalTrials.gov

Summary

Osteoporotic vertebral compression fractures are common in older adults and may present as either acute or chronic fractures. Correctly distinguishing acute from chronic fractures is clinically important because treatment strategies and management decisions differ depending on fracture chronicity. However, differentiating acute and chronic osteoporotic vertebral compression fractures based on imaging findings alone can be challenging in routine clinical practice. This retrospective study aims to develop an intelligent diagnostic system based on computed tomography (CT) images to differentiate acute and chronic osteoporotic vertebral compression fractures. Clinical and imaging data from patients diagnosed with osteoporotic vertebral compression fractures will be collected from the First Affiliated Hospital of Chongqing Medical University and an additional medical center. A deep learning model will be trained to automatically analyze CT images and classify fractures as acute or chronic. The results of this study may help improve the accuracy and efficiency of fracture chronicity assessment using CT images and provide supportive information for clinical decision-making regarding treatment selection in patients with osteoporotic vertebral compression fractures.

Official title: A Deep Learning Model Based on CT Images for Differentiating Acute and Chronic Osteoporotic Vertebral Compression Fractures

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

OBSERVATIONAL

Enrollment

276

Start Date

2025-12-16

Completion Date

2026-01-15

Last Updated

2025-12-31

Healthy Volunteers

No

Interventions

OTHER

No Intervention (Observational Study)

This is a retrospective observational study. No therapeutic, diagnostic, or preventive intervention is assigned as part of the study. All analyses are based on previously acquired clinical and imaging data.

Locations (1)

The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China