Clinical Research Directory
Browse clinical research sites, groups, and studies.
To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage
Sponsor: Asian Institute of Gastroenterology, India
Summary
In adults with walled-off pancreatic necrosis (WON) undergoing endoscopic ultrasound (EUS)-guided transluminal necrosectomy, does early removal of the lumen-apposing metal stent (LAMS) (at 2 weeks or immediately after the last necrosectomy) with placement of a double-pigtail plastic stent (DPT), compared to delayed LAMS removal at 4 weeks without a DPT, result in a lower rate of pancreatic fluid collection (PFC) recurrence or need for reintervention over 12 months.
Official title: A Randomized Controlled Trial To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
408
Start Date
2025-12-25
Completion Date
2028-12-31
Last Updated
2026-01-28
Healthy Volunteers
No
Conditions
Interventions
Standard LAMS Removal with Double-Pigtail Plastic Stent
In the early stent removal arm, LAMS will be removed at 2 weeks followed by placement of a double-pigtail plastic stent (DPT).
Standard LAMS Removal without DPT
In the standard arm, LAMS will be removed at 4 weeks.
Locations (1)
Asian Institute of Gastroenterology
Hyderabad, Telangana, India