Clinical Research Directory

Inclusion Criteria: 1. Age 40 to 74 years, inclusive; men and women. 2. Scheduled for elective screening, diagnostic, or surveillance colonoscopy. 3. In generally good condition, mentally competent, and willing to provide written informed consent. Exclusion Criteria: 1. Known contraindication to colonoscopy or to biopsy. 2. History of colon cancer or previous colonic surgery. 3. Bowel obstruction; confirmed or highly suspected colorectal cancer; inflammatory bowel disease; or active colorectal bleeding. 4. Colorectal polyposis, including a history of familial adenomatous polyposis. 5. Pregnancy or breastfeeding. 6. Participation in another drug or medical device clinical trial within 1 month before enrollment. 7. Any other condition that, in the investigator's judgment, makes the participant unsuitable for this trial. Withdrawal Criteria: 1. Withdrawal of consent by the participant. 2. Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale (BBPS) total score below 6 or any segment score below 2. 3. Failure to reach the cecum. 4. Newly diagnosed active colitis during the procedure.