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NOT YET RECRUITING
NCT07308522
NA

Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis

Sponsor: University of Baghdad

View on ClinicalTrials.gov

Summary

Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque. Electric brushes remove more plaque and reduce gingivitis better than manual ones, and users show better periodontal status. App-connected smart brushes and apps aim to improve adherence. Trials increased plaque reduction and brushing time versus manual brushing, but app layers have not clearly beaten standard power brushes, and microbiological outcomes are rarely reported. Xiaomi's AI-based sonic T501 adds pressure sensing, personalised coaching and coverage tracking, whereas the T302 is a simpler non-connected sonic brush. Streptococcus sanguinis is a health-associated early coloniser; its qPCR-measured relative abundance marks a healthy supragingival profile. It is still unclear whether AI guidance adds extra benefit beyond a standard electric brush in adult gingivitis.

Official title: Clinical ,Microbiological and Compliance Outcomes of AI-based vs Standard Electric and Manual Toothbrushes in Adults With Plaque-Induced Gingivitis: A 6-Week Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

33

Start Date

2026-01-01

Completion Date

2026-06-30

Last Updated

2025-12-29

Healthy Volunteers

No

Interventions

DEVICE

AI toothbrush

Smart toothbrush supported with AI applications to improve toothbrushing experience

DEVICE

Manual toothbrush

Manual toothbrush used as a gold standard control

DEVICE

Electric toothbrush

Electric toothbrush as a second control group

Locations (1)

College of Dentistry, University of Baghdad

Baghdad, Al-Rasafa, Iraq