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RECRUITING
NCT07309354
NA

Tizanidine and Acoustic Reflex

Sponsor: Uşak University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn how the muscle relaxant tizanidine affects the acoustic reflex in adults. The acoustic reflex is a natural protection system of the ear that helps reduce the impact of loud sounds. It is not known whether tizanidine changes how this reflex works. The main question this study aims to answer is: Does taking tizanidine for 1 week change acoustic reflex thresholds in the same person, when comparing before and after treatment? Participants who receive tizanidine will undergo hearing and acoustic reflex tests before treatment and again at the end of the treatment period.

Official title: The Effects of Tizanidine on Acoustic Reflex

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

45

Start Date

2025-07-15

Completion Date

2026-03-15

Last Updated

2025-12-30

Healthy Volunteers

No

Interventions

DRUG

Tizanidine

Participants will receive tizanidine 6 mg orally once daily for 1 week. Standardized audiological testing, including tympanometry and multifrequency acoustic reflex measurements, will be performed before starting treatment and on day 7 at the end of the treatment period to evaluate changes in acoustic reflex thresholds and response patterns.

Locations (1)

Uşak University Faculty of Medicine

Uşak, Merkez, Turkey (Türkiye)