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Hyaluronic Acid in the Treatment of Hyposalivation
Sponsor: Poznan University of Medical Sciences
Summary
The goal of this clinical trial is to learn if drug containing non-crosslinked hyaluronic acid and amino acids solution (Sunecos-200) works to treat hyposalivation in adults. It will also learn about the safety of drug Sunecos-200. The main questions it aims to answer are: * Does Sunecos-200 improve the saliva secretion and improve a life comfort? * What medical problems do participants have when taking Sunecos-200? Researchers will compare drug containing non-crosslinked hyaluronic acid and amino acids solution (Sunecos-200) to a control group (without intervention) to see if drug Sunecos-200 works to treat hyposalivation. Participants will: * Take drug Sunecos-200 by into oral mucosa injection or nothing every two weeks for 4 times. * Visit the clinic once every 2 weeks for checkups and tests * Keep a diary of their symptoms after injection and fill out a primary and final questionary.
Official title: Hyposalivation Treatment With Non-crosslinked Hyaluronic Acid and Amino Acids Solution
Key Details
Gender
All
Age Range
38 Years - 78 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-07-01
Completion Date
2026-01-19
Last Updated
2025-12-30
Healthy Volunteers
No
Interventions
Sunecos-200 Injectable Hyaluronic acid and amino acids solution
In the study group with intervention a total of 2 mL (1 mL on each side) of Sunecos-200 solution (HA and AAs) were injected into the buccal mucosa four times at two-week intervals. The distance between the points of the injections was approximately 10 mm. The total number of injection points per side was 5. Cosmetic syringes (1 ml) and needles 30 G 4 mm were used for injection.
Locations (1)
Department of Periodontology and Oral Mucosa Diseases, Poznan University of Medical Sciences
Poznan, Greater Poland Voivodeship, Poland