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Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy
Sponsor: Sun Yat-sen University
Summary
This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)\<80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy. The investigators conducted a retrospective analysis of cases from their center over the past five years, stratifying patients into Low Pa0₂ Group and Normal Pa0₂ Group based on postoperative oxygen levels and comparing the incidence of anastomotic leakage between the groups. The goal is to establish whether hypoxia is a causative risk factor and whether correcting it can reduce the risk of anastomotic leakage.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
2500
Start Date
2021-01-01
Completion Date
2026-12-01
Last Updated
2026-06-16
Healthy Volunteers
No
Conditions
Locations (6)
Department of Thoracic Surgery, Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China
Cancer Hospital of Shantou University Medical College
Shantou, Guangdong, China
The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital
Shijiazhuang, Hebei, China
Shanghai Chest Hospital
Shanghai, Shanghai Municipality, China
Sichuan Cancer Hospital
Chengdu, Sichuan, China
0817-2598459
Nanchong, Sichuan, China