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Rutin and Vitamin C in Patients With Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
Sponsor: Ain Shams University
Summary
evaluate the combined effects of Rutin and Vitamin C versus Vitamin C alone on selected oxidative stress markers, inflammation, hepatic steatosis regression, and associated metabolic parameters in patients with MASLD
Official title: Evaluation of the Effect of Rutin and Vitamin C in Patients With Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2026-01-01
Completion Date
2027-03-01
Last Updated
2025-12-30
Healthy Volunteers
No
Conditions
Interventions
Rutin + Vitamin C
Type: Drug (Combination therapy) Details: Oral administration of two tablets containing 60 mg Rutin + 160 mg Vitamin C, taken three times daily for 12 weeks.
Vitamin C 500mg
Type: Drug (Single agent) Oral administration of Vitamin C 500 mg, taken twice daily for 12 weeks
Lifestyle Intervention
Mediterranean diet focusing on fruits, vegetables, whole grains, healthy fats, plus structured exercise program for 12 weeks.
Locations (1)
National Hepatology and Tropical Medicine Research Institute (NHTMRI)
Cairo, Egypt