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HELIOS: Human Embryo Illumination to Enhance Development
Sponsor: Columbia University
Summary
Embryos need a lot of energy to grow, but as women get older, the "power plants" of the cells (called mitochondria) don't work as well. This makes it harder for embryos to develop normally. One possible way to help is with a gentle light treatment called photobiomodulation (PBM). This uses a special type of red light that boosts energy production in cells and helps them stay healthy. This study will test whether adding this light treatment during in vitro fertilization (IVF) can improve embryo growth and pregnancy chances.
Key Details
Gender
FEMALE
Age Range
18 Years - 48 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2025-12-03
Completion Date
2028-06-01
Last Updated
2026-03-25
Healthy Volunteers
No
Conditions
Interventions
Photobiomodulation
Photobiomodulation (PBM), also known as low-level light therapy (LLLT), involves the application of low-intensity red or near-infrared (NIR) light to modulate mitochondrial activity.
Locations (1)
Columbia University Fertility Center
New York, New York, United States