Clinical Research Directory
Browse clinical research sites, groups, and studies.
R³ Rehab Pathway Versus Usual Care After Lumbar Radicular Surgery
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
The R³ trial is a multicentre cluster randomized controlled trial evaluating an evidence-based, person-centred rehabilitation pathway for patients undergoing lumbar surgery for radicular pain. The pathway includes structured pre-, peri-, and postoperative rehabilitation, early postoperative mobilization, case management, early return-to-work (RTW) guidance, and patient empowerment. Clusters (hospitals) are randomized to implement the R³ pathway (intervention) or continue usual care (control). The primary aim is to determine whether the R³ pathway reduces time to return to work compared with usual care.
Official title: An Evidence-based Rehabilitation Pathway for Patients Undergoing Surgery for Lumbar Radicular Pain to Promote Return to Work: a Cluster Randomized Trial Comparison With Usual Care.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
480
Start Date
2026-02
Completion Date
2028-05
Last Updated
2026-01-08
Healthy Volunteers
No
Interventions
R³ Rehabilitation Pathway
A structured evidence-based rehabilitation pathway, guided by a case manager, starting preoperatively to 1 year postoperatively, including prehabilitation, perioperative rehabilitation and postoperative rehabilitation, with emphasis on fear reduction by keeping activity restrictions minimal and relevant, eliminating bracing and on active guidance to work resumption.
Locations (16)
ZAS
Antwerp, Belgium
AZ Sint Jan Brugge
Bruges, Belgium
UZ Brussel
Brussels, Belgium
Grand Hôpital de Charleroi
Charleroi, Belgium
Ziekenhuis Geel
Geel, Belgium
ZOL Genk
Genk, Belgium
Jessa Ziekenhuis
Hasselt, Belgium
AZ Herentals
Herentals, Belgium
Jan Yperman ziekenhuis
Ieper, Belgium
AZ Groeninge Kortrijk
Kortrijk, Belgium
UZ Leuven
Leuven, Belgium
Heilig Hart Lier
Lier, Belgium
AZ Sint Maarten Mechelen
Mechelen, Belgium
CSPO
Ottignies, Belgium
AZ Delta Roeselare
Roeselare, Belgium
Centre Hospitalier de Wallonie Picarde
Tournai, Belgium