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Mode of Ventilation During Critical Illness at Multiple Centers
Sponsor: Vanderbilt University Medical Center
Summary
The goal of this clinical trial is to learn whether the choice of ventilator mode for patients on breathing machines in the intensive care unit affects their survival and recovery. To do this, researchers will assign the entire participating intensive care unit to one of the three available ventilator modes, alternating which mode is assigned in random sequence every 2 months. The main question it aims to answer is: Does the choice between volume control, pressure control, and adaptive pressure control affect the number of days that patients are alive and free of the breathing machine?
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
4785
Start Date
2027-07
Completion Date
2030-03
Last Updated
2026-01-02
Healthy Volunteers
No
Interventions
Volume control
Volume control mode for invasive mechanical ventilation
Pressure control
Pressure control mode for invasive mechanical ventilation
Adaptive pressure control
Adaptive pressure control for invasive mechanical ventilation
Locations (1)
Vanderbilt University Medical Center
Nashville, Tennessee, United States