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Antiseptic-Coated Sutures and Pancreatic Fistula Risk After Pancreatoduodenectomy
Sponsor: The Cleveland Clinic
Summary
The purpose of this study is to determine if the use of antiseptic-coated sutures is better than the use of the standard sutures in preventing postoperative fistulas within 90 days after pancreatoduodenectomy.
Official title: Does Antiseptic Coated Suture Reduce Pancreatic Fistula Rate After Pancreatoduodenectomy: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
436
Start Date
2026-01-13
Completion Date
2031-02
Last Updated
2026-01-21
Healthy Volunteers
No
Conditions
Interventions
Standard (non-antiseptic coated) suture will be used.
This is an operation to treat tumors and other conditions in the pancreas, small intestine, and bile ducts. It involves removing the head of the pancreas, the first part of the small intestine, the gallbladder, and the bile duct. Part of the procedure involves sutures. A suture(s) is a stitch or row of stitches holding together the edges of a wound or surgical incision
Triclosan/antiseptic -coated suture
Triclosan/antiseptic -coated suture will be used. Ethicon PDSTM Plus Antibacterial Suture will be used at the layer of the pancreatojejunostomy and for the duration of the case.
Locations (3)
Cleveland Clinic Akron
Akron, Ohio, United States
Cleveland Clinic
Cleveland, Ohio, United States
Cleveland Clinic Fairview Hospital
Fairview, Ohio, United States