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Autologous Tenon's Capsule Graft for Refractory Macular Holes
Sponsor: Benha University
Summary
This prospective interventional study evaluates the anatomical and functional outcomes of autologous Tenon's capsule grafting in patients with refractory full-thickness macular holes. Eligible patients include those with chronic large macular holes (\>400 µm) or persistent holes following prior pars plana vitrectomy with internal limiting membrane peeling and gas tamponade. Anatomical closure will be assessed using spectral-domain optical coherence tomography, and functional outcomes will be evaluated by best-corrected visual acuity over a 3-month follow-up period.
Official title: Visual and Anatomical Outcomes of Autologous Tenon's Capsule Graft for Refractory Macular Holes
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-12-14
Completion Date
2026-06-03
Last Updated
2026-01-06
Healthy Volunteers
No
Conditions
Interventions
Autologous Tenon's Capsule Graft Placement
Participants will undergo 23-gauge pars plana vitrectomy. Autologous Tenon's capsule tissue will be harvested through conjunctival peritomy, trimmed appropriately, and placed into the macular hole using intraocular forceps. Perfluorocarbon liquid may be used for graft stabilization, followed by silicone oil tamponade. Silicone oil removal is planned after 8-12 weeks.
Locations (1)
Benha University
Banhā, Benha, Egypt