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Advanced PRF vs PRF for Gap Filling in Immediate Implants
Sponsor: Beni-Suef University
Summary
Study type: Clinical Trial Goal: The goal of this clinical trial is to learn if Advanced Platelet-Rich Fibrin (A-PRF) versus traditional Platelet-Rich Fibrin (PRF) can improve bone healing and soft tissue outcomes in patients undergoing immediate dental implant placement. Main questions it aims to answer: Does A-PRF provide greater buccal bone preservation compared to PRF after immediate implant placement? Does A-PRF improve soft tissue healing and reduce postoperative complications compared to PRF? Comparison group: Researchers will compare A-PRF to PRF as a gap-filling material in immediate implants to see if A-PRF results in better bone and soft tissue outcomes. Participants will: Undergo tooth extraction followed by immediate implant placement Receive either A-PRF or PRF as the gap-filling material in the implant site Have CBCT scans at baseline and 6 months to measure bone thickness Have clinical assessments of soft tissue healing and implant stability Attend follow-up visits at 1 week, 1 month, 3 months, and 6 months post-surgery
Official title: Comparison of Advanced Platelet Rich Fibrin Versus Platelet Rich Fibrin as a Gap Filling Material in Immediate Implant Placement
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2025-06-25
Completion Date
2026-02-15
Last Updated
2026-01-06
Healthy Volunteers
No
Conditions
Interventions
Immediate Dental Implant and A-PRF
Arm 1: Advanced Platelet-Rich Fibrin (A-PRF) Participants will have a tooth extracted, the socket cleaned, and A-PRF prepared from their blood placed in the socket as a gap-filling material before immediate implant placement. Follow-up visits will assess bone and soft tissue healing and implant stability.
Immediate dental implant and PRF
Arm 2: Platelet-Rich Fibrin (PRF) Participants will have a tooth extracted, the socket cleaned, and traditional PRF prepared from their blood placed in the socket as a gap-filling material before immediate implant placement. Follow-up visits will assess bone and soft tissue healing and implant stability.
Locations (1)
Delta University For Science And Technology
Al Mansurah, Egypt