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RECRUITING
NCT07320924
NA

Patient-specific Reconstruction Plate for Segmental Mandibular Defects

Sponsor: Alexandria University

View on ClinicalTrials.gov

Summary

The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require extensive intraoperative bending, often resulting in imperfect adaptation, press-to-contact fixation, and residual stresses that increase the risk of hardware fatigue and fracture. Recent advances in computer-aided design and manufacturing (CAD/CAM) and virtual surgical planning (VSP) have improved precision in maxillofacial reconstruction. Patient-Specific Reconstruction Plates (PSRP), developed from virtual planning and patient-specific anatomical data, offer a bespoke contour adaptation, predictable screw positioning, and elimination of press-fit deformation. This customization improves alignment, mechanical stability, and long-term outcomes.

Official title: Patient-specific Reconstruction Plate for Alloplastic Bridging of Segmental Mandibular Defects. A Clinical and Radiographic Study.

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

14

Start Date

2025-01-01

Completion Date

2026-08-30

Last Updated

2026-01-06

Healthy Volunteers

No

Interventions

DEVICE

Patient specific reconstruction plate

Patient specific reconstruction plate

Locations (1)

Faculty of Dentistry, Alexandria University

Alexandria, Alexandria Governorate, Egypt