Clinical Research Directory

Inclusion Criteria: * Voluntary written informed consent of the participant has been obtained prior to any screening procedures * Age 18-43 * Planning to undergo MAR (eg, IUI, IVF, ICSI) - Physically able to cycle for cardiopulmonary exercise testing (CPET) Exclusion Criteria: * Any reduction in general state of health preventing from performing hormonal stimulation for MAR * Absolute and relative contraindications for cardiopulmonary exercise testing (CPET) - No pregnancy at initial screening - Current illicit drug abuse including daily marijuana and CBD consumption (alcohol ≤2 drinks per day allowed) * Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease) * Severe renal impairment (e.g. estimated glomerular filtration rate \<30 ml/min/m2) * Known liver cirrhosis or other severe liver impairment * Uncontrolled dysthyroidism * Uncontrolled hypertension * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, etc.