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RECRUITING
NCT07322094
PHASE1/PHASE2

CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer

Sponsor: TORL Biotherapeutics, LLC

View on ClinicalTrials.gov

Summary

A Phase 1B/2 Study to Investigate the Safety and Efficacy of TORL-1-23 with Chemotherapy Given Before Initial Surgery in Women with Advanced Stage Ovarian Cancer

Official title: CATALINA-4: Phase 1B/2 Study of TORL-1-23 With Neoadjuvant Chemotherapy and Interval Cytoreductive Surgery in Newly Diagnosed Patients With Advanced Stage Ovarian Cancer

Key Details

Gender

FEMALE

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-12-10

Completion Date

2028-01

Last Updated

2026-01-07

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

TORL-1-23 and paclitaxel

TORL-1-23 and paclitaxel

COMBINATION_PRODUCT

TORL-1-23 and carboplatin

TORL-1-23 and carboplatin

COMBINATION_PRODUCT

TORL-1-23, paclitaxel, and carboplatin

TORL-1-23, paclitaxel, and carboplatin

Locations (1)

UCLA

Los Angeles, California, United States