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Growth Hormone and Dehydroepiandrosterone Role in Vitro Fertilization
Sponsor: Beni-Suef University
Summary
The goal of this study is to evaluate the role of Somatropin and Dehydroepiandrosterone (DHEA) on ovarian reserve parameters and intracytoplasmic sperm injection (ICSI) outcome in poor ovarian responder. The main question it aims to answer is: Which intervention is more effective in increasing number and size of follicles? Participants will be followed 1 month before starting induction in growth hormone and 12 weeks for DHEA and through intracytoplasmic sperm injection (ICSI) cycle.
Official title: Growth Hormone and Dehydroepiandrosterone Effect on Poor Ovarian Reserve Patients During in Vitro Fertilization
Key Details
Gender
FEMALE
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
165
Start Date
2025-10-10
Completion Date
2026-11-12
Last Updated
2026-01-07
Healthy Volunteers
No
Conditions
Interventions
Somatropin (4IU for 1 month) plus, folic acid 400 mcg per day.
Patients will receive Somatropin (4IU for 1 month)1 S.C injection every 3 days for at least 1 month plus, folic acid 400 mcg per day.
DHEA plus folic acid 400mcg per day
Patients will receive DHEA 50 mg twice per day for 12 weeks plus folic acid 400mcg per day
control group
Patients will receive folic acid 400 mcg per day
Locations (1)
Beni-Suef University Hospital
Banī Suwayf, Beni Suweif Governorate, Egypt