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Development of Optical Biometer
Sponsor: Cassini Technologies
Summary
The Helioscope (Cassini Technologies B.V.) is a novel device under development that aims at combining LED-based corneal topography and SS-OCT to provide accurate and fast measurements of both the corneal shape and the ocular biometry. To that end, the hardware and software of the Cassini color-LED topographer (Cassini Technologies B.V.) is combined with a novel SS-OCT device. While the new Helioscope can largely be evaluated using data acquired with healthy eyes, one of its main use-cases is providing input for IOL power formulae for cataract surgery. Thus, it is essential that the device can perform measurements in eyes with (dense) cataract. As cataract changes the optical properties of the crystalline lens and the OCT measurement is optical, this is not a given. This study therefore seeks a dataset of Helioscope measurements performed in eyes with cataract that can be used to develop the software algorithms of the Helioscope.
Official title: Development of a Next-Generation Optical Biometer for Eyes With Cataract
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-11-07
Completion Date
2026-03-30
Last Updated
2026-01-08
Healthy Volunteers
No
Conditions
Interventions
New Investigational Optical Biometer (Device)
Investigational optical biometer used to obtain axial length, keratometry, anterior chamber depth, lens thickness, and total corneal astigmatism. Device is being evaluated for measurement accuracy and agreement.
Comparator Device A (Cassini Ambient)
FDA-cleared corneal topographer used as a reference standard comparator for keratometry.
omparator Device B (Argos)
FDA-cleared optical biometer used as a second comparator to assess agreement and measurement differences.
Locations (1)
Bishop Eye Center
Hilton Head Island, South Carolina, United States