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Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury
Sponsor: Tamas Vegh, MD
Summary
The aim of this study is to longitudinally monitor dynamic changes in the gut microbiome following severe burn injury using fecal samples. Under standard nutritional protocols and intensive care management, serial fecal sampling is performed to assess alterations in microbiome diversity and composition, as well as the indirect effects of these changes on measurable inflammatory biomarkers, endocrine, hematological, immunological, and other organ-specific parameters, the clinical course, and patient outcomes.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2023-12-01
Completion Date
2026-12-31
Last Updated
2026-01-09
Healthy Volunteers
No
Locations (1)
University of Debrecen, Department of Anesthesiology and Intensive Care
Debrecen, Hajdú-Bihar, Hungary