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COMPLETED
NCT07329907
PHASE2

Combination Therapy for Warts: Candida Antigen vs. Topical Keratolytic

Sponsor: Benha University

View on ClinicalTrials.gov

Summary

Objective: To compare the efficacy, safety, and recurrence rates of topical salicylic acid/lactic acid (SA/LA) monotherapy (Group A), intralesional Candida antigen (CA) monotherapy (Group B), and their combination (Group C) for the treatment of warts.

Official title: Comparative Efficacy of Topical Salicylic Acid/Lactic Acid, Intralesional Candida Antigen, and Their Combination in the Treatment of Warts: A Randomized, Assessor-Blinded, Controlled Trial

Key Details

Gender

All

Age Range

5 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

126

Start Date

2023-12-01

Completion Date

2024-12-30

Last Updated

2026-08-04

Healthy Volunteers

No

Interventions

DRUG

Salicylic Acid/Lactic Acid Topical Solution

Patients receive topical application of Salicylic Acid 40% and Lactic Acid 16% once daily for up to 6 weeks.

BIOLOGICAL

Candida Antigen Intralesional Injection

Patients receive intralesional injection of Candida Antigen (0.1-0.3 mL) every 2 weeks for up to 6 sessions.

COMBINATION_PRODUCT

Candida Antigen and Salicylic Acid/Lactic Acid

Patients receive intralesional injection of Candida Antigen (0.1-0.3 mL) every 2 weeks for up to 6 sessions, with topical Salicylic Acid 40% and Lactic Acid 16% applied in between.

Locations (1)

Outpatient Clinic of Dermatology, Venereology and Andrology Department at Benha University Hospitals

Banhā, Qalyubia Governorate, Egypt