Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
Sponsor: Zagazig University
Summary
In this study the participants aim to Compare The Effect of Intravenous Combination Dexmedetomidine \_ Ketamine versus Dexmedetomidine on Post-Operative Analgesia In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia regarding efficacy, hamemodynamic stability, outcomes and adverse effects.
Official title: The Effect of Intravenous Combination Dexmedetomidine - Ketamine Versus Dexmedetomidine on Post-Operative Analgesia in Patients Undergoing Vaginal Hysterectomy Under Spinal Anesthesia
Key Details
Gender
FEMALE
Age Range
21 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-01-20
Completion Date
2026-06-30
Last Updated
2026-01-09
Healthy Volunteers
Yes
Interventions
Dexmedetomidine
Intravenous dexmedetomidine 0.5 µg/kg diluted with normal saline to a volume of 10 ml solution over 10 min followed by 0.5 µg/kg/h infusion.
Ketamine
Intravenous ketamine 0.2 mg/kg diluted with normal saline to a volume of 10 ml solution over 2-3 min followed by 0.2 mg/kg/hr infusion.
Saline (0.9% NaCl)
intravenous normal saline 10ml of solution over 2-3min followed by 0.2 mg/kg/hr infusion as placebo