Clinical Research Directory
Browse clinical research sites, groups, and studies.
Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo)
Sponsor: Centre Hospitalier Universitaire de la Guadeloupe
Summary
Metabolic Dysfunction Associated Liver Disease (MASLD) is associated with metabolic syndrome, and PNPLA3 variants are known to be implicated in intrahepatic lipid accumulation and linked to lipotoxicity. Analysis of PNPLA3 polymorphisms in an overseas territories population of MASLD would be interesting to describe their profile susceptibility to develop Metabolic dysfunction associated steatohepatitis (MASH).
Official title: Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2025-11-26
Completion Date
2027-11-28
Last Updated
2026-01-09
Healthy Volunteers
No
Locations (3)
Centre Hospitalier Universitaire de la Guyane
Cayenne, French Guiana
CHU de la Guadeloupe
Pointe-à-Pitre, Guadeloupe
Centre Hospitalier Universitaire de la Réunion
Saint-Denis, Reunion