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NCT07331116

Echocardiography Findings in Patients With Myocardial Fibrosis and Severe Aortic Stenosis

Sponsor: Norwegian University of Science and Technology

View on ClinicalTrials.gov

Summary

Patients with aortic stenosis waiting for aortic valve repair were investigated with echocardiography preoperatively, and a myocardial biospy was taken during the operation. The investigators aim to perform a retrospective analysis of these data, to look for correlations between biopsy-verified myocardial fibrosis and echocardiography parameters. The patients also had cardiac magnetic resonance imaging performed, for a non-invasive quantification of myocardial fibrosis.

Official title: Correlations Between Biopsy Verified Myocardial Fibrosis and Echocardiography Parameters in Patients With Severe Aortic Stenosis

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

22

Start Date

2014-04-10

Completion Date

2021-03-01

Last Updated

2026-04-17

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Transthoracic echocardiography

Transthoracic echocardiography, performed close in time to the endomyocardial biopsy taken during aortic valve replacement procedure

DIAGNOSTIC_TEST

Cardiac magnetic resonance imaging

Cardiac magnetic resonance imaging was taken on selected patients without contraindications. The CMR protocol was changed midway during study inclusions (May 2017), in order to better be able to quantify myocardial fibrosis.

Locations (1)

Norwegian University of Science and Technology

Trondheim, Norway