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ACTIVE NOT RECRUITING
NCT07331688
PHASE1/PHASE2

CMTS0515-auWMT for Radiation Enteritis

Sponsor: The Second Hospital of Nanjing Medical University

View on ClinicalTrials.gov

Summary

This is a randomized controlled trial to explore the exploring the non-inferiority of CMTS0515-augmented WMT compared to WMT.

Official title: CMTS0515 - Augmented Washed Microbiota Transplantation Versus Washed Microbiota Transplantation in Radiation Enteritis: A Randomized, Double-Blind, Non-inferiority Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-12-08

Completion Date

2030-12-31

Last Updated

2026-01-12

Healthy Volunteers

No

Interventions

OTHER

CMTS0515-augmented washed microbiota transplantation

Lyophilized CMTS0515 is added to washed microbiota suspension and administered via mid-gut or colonic transendoscopic enteral tube.

OTHER

Washed Microbiota Transplantation

Washed microbiota suspension delivered through mid-gut and lower-gut transendoscopic enteral tube.

Locations (1)

Department of Microbiota Medicine & Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China