Clinical Research Directory
Browse clinical research sites, groups, and studies.
Efficacy and Safety of Probiotics for Anxiety Depression
Sponsor: Moon (Guangzhou) Biotechnology Co., Ltd.
Summary
This randomized, double-blind, placebo-controlled study will enroll 60 individuals with mild-to-moderate anxiety depression. Following a 3-month intervention and a 1-month follow-up period, the study aims to: 1) evaluate the efficacy of probiotics by comparing anxiety, depression, and sleep scores to baseline; and 2) investigate the safety and underlying mechanisms by analyzing changes in serum biomarkers, gut microbiota, and related metabolites.
Official title: A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Clinical Efficacy and Safety of Probiotics in Participants With Anxiety Depression
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-03-01
Completion Date
2027-02-28
Last Updated
2026-01-15
Healthy Volunteers
No
Conditions
Interventions
Probiotic
Participants receive Probiotic product once daily by oral, 60B CFU/day for 3 months.
Placebo
Participants receive Placebo once daily by oral for 3 months.
Escitalopram
Participants receive Escitalopram Oxalate Tablets once daily by oral, 10mg/day for 3 months.
Locations (1)
The First Affiliated Hospital of Guangdong Pharmaceutical University
Guangzhou, Guangdong, China