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NOT YET RECRUITING
NCT07331987
NA

Efficacy and Safety of Probiotics for Anxiety Depression

Sponsor: Moon (Guangzhou) Biotechnology Co., Ltd.

View on ClinicalTrials.gov

Summary

This randomized, double-blind, placebo-controlled study will enroll 60 individuals with mild-to-moderate anxiety depression. Following a 3-month intervention and a 1-month follow-up period, the study aims to: 1) evaluate the efficacy of probiotics by comparing anxiety, depression, and sleep scores to baseline; and 2) investigate the safety and underlying mechanisms by analyzing changes in serum biomarkers, gut microbiota, and related metabolites.

Official title: A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Clinical Efficacy and Safety of Probiotics in Participants With Anxiety Depression

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-03-01

Completion Date

2027-02-28

Last Updated

2026-01-15

Healthy Volunteers

No

Interventions

DRUG

Probiotic

Participants receive Probiotic product once daily by oral, 60B CFU/day for 3 months.

DRUG

Placebo

Participants receive Placebo once daily by oral for 3 months.

COMBINATION_PRODUCT

Escitalopram

Participants receive Escitalopram Oxalate Tablets once daily by oral, 10mg/day for 3 months.

Locations (1)

The First Affiliated Hospital of Guangdong Pharmaceutical University

Guangzhou, Guangdong, China