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RECRUITING
NCT07332234

Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies

Sponsor: Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"

View on ClinicalTrials.gov

Summary

Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.

Official title: Utility of Optic Nerve Ultrasonography in Assessing Cerebral Inflammation and Intracranial Hypertension in Patients With Cerebral Impairment

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2025-12-01

Completion Date

2027-12-01

Last Updated

2026-01-12

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Optic Nerve Sheath Diameter

Ultrasonographic measurement of the optic nerve sheath diameter

Locations (2)

Fundeni Clinical Institute

Bucharest, Bucharest, Romania

"Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical Diseases

Bucharest, Bucharest, Romania