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RECRUITING
NCT07332455
PHASE1/PHASE2

First-Time-in-Human Study of GSK5471713 in Adults With mCRPC

Sponsor: GlaxoSmithKline

View on ClinicalTrials.gov

Summary

This first-time-in-human study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, preliminary clinical activity, and establish the benefit/risk of GSK5471713 given as a monotherapy in mCRPC.

Official title: A Phase 1/2 First-Time-in-Human, Open-label, Multicenter, Dose Escalation and Dose Optimization Study of GSK5471713 in Adult Participants With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Key Details

Gender

MALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

54

Start Date

2026-02-10

Completion Date

2030-03-26

Last Updated

2026-02-19

Healthy Volunteers

No

Interventions

DRUG

GSK5471713

GSK5471713 will be administered at different dose levels based on the dose escalation study design

Locations (3)

GSK Investigational Site

Grand Rapids, Michigan, United States

GSK Investigational Site

West Valley City, Utah, United States

GSK Investigational Site

Montreal, Quebec, Canada